A Reducing Substance in Brain Tissue

Identification of substance P precursor forms in human brain tissue.

Substance P prohormones were identified in the caudate nucleus, hypothalamus, and substantia nigra of human brain. A polypeptide fraction of acidic brain extracts was fractionated on Sephadex G-50. The lyophilized fractions were sequentially treated with trypsin and a substance P-degrading enzyme with strong preference toward the Phe7-Phe8 and Phe8-Gly9 bonds. The released substance P(1-7) frag...

Comparison of Residential and Therapeutic Community Centers in Preventing Substance Abuse Recurrence and Reducing Self-destructive Behaviors of Substance Users

A note on the identity of the indophenol-reducing substances in brain tissue.

HARRIS [1933] concluded from the results of biological tests that only about one-third of the material in Jensen rat sarcoma which reduces 2:6-dichlorophenolindophenol is ascorbic acid. Later Young & Mitolo [1934] and Mitolo [1934] brought forward evidence which they believed to indicate that brain tissue also contains an indophenol-reducing factor (I.F.) which is not ascorbic acid. Recent inve...

W1: Neural Tissue Engineering Strategies in Traumatic Brain Injury Therapies

لطفاً به چکیده انگلیسی مراجعه شود.

Reducing the harm of adolescent substance use.

DES HAUSSES RÉCENTES DE LA TOXICOMANIE CHEZ LES ADOLESCENTS attirent l’attention sur des programmes scolaires d’éducation sur les drogues. On a remis en question l’efficacité des programmes classiques, et des chercheurs préconisent de nouvelles méthodes fondées sur les principes de la réduction du préjudice. Une stratégie de réduction du préjudice reconnaît qu’il est irréaliste d’essayer de pré...